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National Public Radio (NPR) Covers CAAT's Mini-Brain Research

Some tiny clusters of brain cells grown in a lab dish are making big news at this week's Society for Neuroscience meeting in San Diego. At a Sunday press conference at the neuroscience meeting, researchers said minibrains are helping them figure out how the Zika virus can disrupt human brain formation in the early stages of fetal development.Thomas Hartung is interviewed. 
Full Article on NPR


Mini-Brains Made to Order: Cell-Culturing Technique Developed by JHSPH Scientists Could Revolutionize Neurological Drug Development

From the Johns Hopkins Bloomberg School of Public Health Yearbook

“Ninety-five percent of drugs that look promising when tested in animal models fail once they are tested in humans at great expense of time and money,” says Thomas Hartung, MD, PhD, the Doerenkamp-Zbinden Professor and Chair for Evidence-based Toxicology at the Bloomberg School.

There are myriad reasons why seemingly promising drugs fail when tested on humans, but the most intractable problem is also the most obvious. “While rodent models have been useful,” observes Hartung, “we are not 150-pound rats.”
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CAAT YouTube Channel

CAAT 25th Anniversary Symposium Video

Part 1. Introductory remarks by James D. Yager, PhD and Michael J. Klag, MD, MPH, dean of the Johns Hopkins Bloomberg School of Public Health (16.4 MB QuickTime movie)
WATCH

Part 2. Alan M. Goldberg; Remembering Bill Russell video tribute (52 MB Quicktime movie)
WATCH

CAAT Video

CAAT: 25 Years of Humane Science Documentary (3-part documentary produced for CAAT's 25th Anniversary Symposium)

"Remembering Bill Russell" video tribute

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