The Center for Alternatives to Animal Testing is an academic center affiliated with the Division of Toxicological Sciences in the Department of Environmental Health Sciences of the Johns Hopkins University Bloomberg School of Public Health.
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A Tissue Culture Model of the Human Corneal Epithelium
Marcia M. Jumblatt, PhD
Eye Research Institute, Boston, Massachusetts
Marcia M. Jumblatt and Arthur H. Neufeld, MD, of the Eye Research Institute, Boston, received a new CAAT grant to study wound healing in human corneal cells grown in vitro. They already have studied this phenomenon in rabbit corneal cultures.
An eye irritation test based on human corneal cultures probably would be quicker, cheaper, and more accurate than the Draize eye test, in which potential irritants are placed in the eyes of live rabbits.