The Center for Alternatives to Animal Testing is an academic center affiliated with the Division of Toxicological Sciences in the Department of Environmental Health Sciences of the Johns Hopkins University Bloomberg School of Public Health.

 

Johns Hopkins School of Public Health

Research Grants 1986-1987

Development of Monospeicfic Enzyme Immunoassay for Botulinum Toxins Using Affinity Chromatography and Hybridoma Technology

Manoucherhe Dezfulian, PhD
Johns Hopkins School of Medicine, Baltimore, Maryland

Dezfulian used CAAT funding to develop an in vitro test for infant botulism. He will refine the test to make it more accurate and to apply it to other kinds of botulism, a disease caused by poisons from bacteria that sometimes contaminate food. He believes the new test will be able to replace the currently used mouse assay, reducing both costs and the time required for diagnosis and the start of life-saving treatment.