The Center for Alternatives to Animal Testing is an academic center affiliated with the Division of Toxicological Sciences in the Department of Environmental Health Sciences of the Johns Hopkins University Bloomberg School of Public Health.

 

Johns Hopkins School of Public Health

Research Grants 1986-1987

Irritancy Responses of Corneal and Conjunctival Cell Cultures

Dale R. Meyer, PhD
University of Texas Southwestern Medical School, Dallas, Texas

Meyer will try to develop a battery of in vitro assays using three kinds of rabbit and human eye cells. The battery will be used to study how drugs and other chemicals affect cells. A battery of assays should provide more information about the nature of toxicity than any single in vitro method would. Toxicologists generally believe that the Draize rabbit-eye test will be replaced not by a single in vitro test but by a battery of tests.