The Center for Alternatives to Animal Testing is an academic center affiliated with the Division of Toxicological Sciences in the Department of Environmental Health Sciences of the Johns Hopkins University Bloomberg School of Public Health.

 

Johns Hopkins School of Public Health

Research Grants 1987-1988

Retinoic Acid Modulated Transcriptional Response and Anti-Inflammation

P.C. Huang, PhD
The Johns Hopkins School of Public Health, Baltimore, Maryland

Huang will investigate how cells fight inflammation. He will test whether an anti-inflammatory drug known to be effective against arthritis induces the production of metallothionein, which he suspects is used by cells in battling inflammatory agents. Among other things, Huang will look at RNA molecules that carry information concerning metallothionein synthesis from the gene.