The Center for Alternatives to Animal Testing is an academic center affiliated with the Division of Toxicological Sciences in the Department of Environmental Health Sciences of the Johns Hopkins University Bloomberg School of Public Health.
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Ruben Adler, MD
The Johns Hopkins School of Medicine, Baltimore, Maryland
Adler is continuing his analysis of the cell-specific mechanism of excitatory amino acid neurotoxins in well-defined culture of chick embryo and mouse retinal neurons and photoreceptors. The dose-response characteristics of the toxins on specific cells will allow use of the cultures as a bioassay. Adler also is investigating the involvement of endogenous neurotransmitters made by the cultured cells.