The Center for Alternatives to Animal Testing is an academic center affiliated with the Division of Toxicological Sciences in the Department of Environmental Health Sciences of the Johns Hopkins University Bloomberg School of Public Health.
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Research Grants 1990-1991
Development of an Explant System for the Study of Defined Progenitor Populations
S. E. Pfeiffer, PhD
University of Connecticut School of Medicine, Farmington, Connecticut
Pfeiffer proposes developing a system of mouse brain explants for study of neuron remyelination. Subpopulations of oligodendroglia will be introduced in the cultures and their migration and differentiation charted via a variety of measures, including immunological markers.