Skip Navigation
Johns Hopkins Bloomberg School of Public HealthCAAT

Book Launch: Animal Experimentation: Working Towards a Paradigm Change

Friday, November 30th, 2018
9am - 5pm

The Johns Hopkins Bloomberg School of Public Health
615 N. Wolfe St.
Baltimore, MD 21205
Feinstone Hall (E2030)

Tune Into the Live Stream Here

Copyright 2018 Anwen Keeling
Above: Boo, a long-tailed macaque used in neurology experiments who was rescued
in 2009 and now lives at the Lakeview Monkey Sanctuary in the U.K.
© Copyright Anwen Keeling

Animal Experimentation: Working Towards a Paradigm Change

(K. Herrmann and K. Jayne, eds., Brill Human Animal Studies Series, Vol. 22) 
Hosted by the Center for Alternatives to Animal Testing

Russell and Burch introduced the principles of replacement, reduction, and refinement of animal experimentation in 1959 in their groundbreaking book, The Principles of Humane Experimental Technique (Russell and Burch, 1959). Their highest goal was to avoid the use of animals wherever possible, and—in cases where animals were still deemed indispensable—to significantly enhance their treatment while also improving the quality of research and testing. There is growing recognition that a focus on human-relevant data is needed for the understanding and possible treatment of chronic, complex diseases, many of which are not well understood and, thus, cannot be readily modeled in other animals. The technology revolution has greatly changed the field of life sciences and now provides us with tools enabling a shift away from animal experimentation. The 51 experts who contributed to Animal Experimentation: Working Towards a Paradigm Change review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards the continuing replacement and eventual elimination of animals used in science as envisioned by Russell and Burch almost 60 years ago. 

At this book launch event, several of our mostly North America-based authors will give talks based on their book chapters. Please see the program (below) for details. 


Please email Kathrin Herrmann ( to register by November 27th. There is no cost for the event. 


9 am
Registration and coffee

10 am
 Welcome and introduction
Thomas HartungKathrin Herrmann

10:10 am
Jim Keen
Wasted money in United States biomedical and agricultural animal research

10:55 am
Kathrin Herrmann
Refinement on the way towards replacement: Are we doing what we can?

11:35 am
Shalin Gala
Modernizing biomedical training: replacing live animal laboratories with human simulation

12:20 pm
Adam See
Behavioral research on captive animals: ethical concerns

12:50 pm
Lunch Break

1:50 pm
Laura Alvarez (presenting for Katy Taylor)
Recent developments in alternatives to animal testing                                               

2:35 pm
Lisa Kramer
The scientific problems with using non-human animals to predict human response to drugs and disease, plus a proposed debate format 

3:30 pm
Thomas Hartung
Research and testing without animals: where are we now and where are we heading?

4:15 pm
John Gluck
Evidence over interest 

4:30 pm
Thomas Hartung, Kathrin Herrmann


Shalin Gala is Vice President, International Laboratory Methods at People for the Ethical Treatment of Animals (PETA). Gala and co-authors’ scholarly work focuses on the transition from animal use to human simulation models for various disciplines, including biomedical education and military medical training, and his work has appeared in medical journals such as Military Medicine and Simulation in Healthcare. Gala has brokered academic, industry, and medical expert coalitions to advance the goal of modernizing medicine without harming animals. For more than 14 years, he has worked on and overseen successful legislative and campaign efforts that have led to the successful replacement and/or reduction of animal use globally in military pre-hospital training, chemical casualty drills, pediatric intubation exercises, undergraduate and postgraduate medical curricula, and surgical training courses. Gala holds a Bachelor’s degree in Anthropology from Washington University in St. Louis, US.

John P. Gluck is Professor Emeritus at the University of New Mexico and Research Professor at the Kennedy Institute of Ethics, Georgetown University, United States. He earned his PhD in comparative psychology and experimental psychopathology at the University of Wisconsin, under the mentorship of Harry F. Harlow. Gluck completed a Clinical Psychology Fellowship at the University of Washington, Department of Psychiatry, and a Fellowship in Bioethics at Georgetown University and the National Institutes of Health. His writing is concerned with the missing ethical elements of animal research justification and includes the books, Applied Ethics in Animal Researchpublished by Purdue University, and The Human Use of Animals: Case Studies in Ethical Choice,published by Oxford University Press and co-authored with Tom Beauchamp, F. Barbara Orlans, Rebecca Dresser, and David Morton. In 2016, the University of Chicago published his memoir Voracious Science and Vulnerable Animals: A Primate Scientist’s Ethical Journey.

Thomas Hartung, MD, PhD, is the Doerenkamp-Zbinden Chair for Evidence-based Toxicology with a joint appointment for Molecular Microbiology and Immunology at the Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States. He holds a joint appointment as Professor for Pharmacology and Toxicology at the University of Konstanz, Germany. Hartung is the Director of the Centers for Alternatives to Animal Testing (CAAT) at both universities. As Principal Investigator, he heads the Human Toxome Project funded by the National Institutes of Health, Transformative Research Grant. Hartung is the former Head of the European Commission’s Centre for the Validation of Alternative Methods (ECVAM), Ispra, Italy, and has authored more than 500 scientific publications.

Kathrin Herrmann is a veterinarian and assistant scientist at the Center for Alternatives to Animal Testing (CAAT), at the Johns Hopkins Bloomberg School of Public Health in Baltimore, MD, USA. She is a Diplomate of the European College of Animal Welfare and Behavioural Medicine. For almost a decade, Herrmann worked as a federal inspector of animal experimentation in Germany and frequently witnessed the limitations and shortcomings of animal protection laws, leading to her determination that the current regulatory system does not properly safeguard animals. She decided to initiate this book project to highlight the problems associated with animal use in science and to show ways to work towards a paradigm change. 

Jim Keen, Professor, School of Veterinary Medicine & Biomedical Sciences, University of Nebraska-Lincoln, has been an academic and the US government veterinary and biomedical researcher for 27 years. His research emphasis is infectious and zoonotic livestock diseases. As an epidemiologist, his research is observational, i.e., study of disease in its natural habitat—even when that “natural habitat” is a beef feedlot, the most unnatural bovine environment ever conceived. He began a slow conversion from industrial-animal agricultural supporter, apologist, and enabler to a livestock well-being advocate in 2009. 

Lisa Kramer, Professor of Finance at the University of Toronto, has also been a visiting scholar in the Department of Psychology at Stanford University and the Rady School of Management at the University of California, San Diego. She graduated in 1998 with a PhD in finance from the University of British Columbia. In addition to her primary areas of research in finance and behavioral economics, Kramer is interested in the application of multidisciplinary insights from academic research to the practice of animal advocacy. 

Adam See is a doctoral candidate in philosophy at the City University of New York and an adjunct professor of Environmental Ethics at the New Jersey Institute of Technology. His current written work focuses on contemporary intersections between animal ethics and animal cognition, as well as communication and collaboration in great apes. The subject matter of his most recent academic presentations has been issues of animal experimentation, particularly relating to the ethics of behavioral research on non-human primates.

Laura Alvarez is Science Advisor at Cruelty Free International (formerly the British Union for the Abolition of Vivisection [BUAV]) where she works to ensure that the organisation’s call to end animal testing is supported by sound scientific argument. She has a BSc in biomedical sciences from Royal Holloway, University of London, United Kingdom (UK), and an MSc in clinical microbiology from Queen Mary University of London, UK. She previously worked as a veterinary microbiologist for the UK government’s Animal Health and Veterinary Laboratories Agency where her focus was on the development and validation of new in vitro test systems for the efficacy of disinfectants against clinically important viruses.Note: Laura will be presenting for Katy Taylor. 


Please email Kathrin Herrmann ( to register or for further information.