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10th Annual 3Rs Symposium: The 3Rs in Action!

10th Annual 3Rs


ONLINE EVENT

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Wednesday & Thursday, May 17-18, 2023 | 8:30 AM to 5:00 PM EST

This event will be submitted for RACE Credits.

This symposium will focus on reduction, refinement, and replacement methods to improve laboratory animal welfare while maintaining or improving scientific results. It is jointly organized by the Center for Alternatives to Animal Testing, Johns Hopkins University Bloomberg School of Public Health, the Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, the USDA’s Animal Welfare Information Center (AWIC) at the National Agricultural Library, and the Office of Laboratory Animal Welfare, National Institutes of Health.

Sessions are designed for investigators, laboratory animal veterinarians, care staff, and IACUC members and staff. Residents, students, and postdocs are also welcome!

Please join us online as we learn from the speakers and each other! There will be opportunities built into the program for attendees to ask questions, comment, or offer suggestions. We look forward to seeing you there!

NOTE: If you need sign language interpreter please let us know.

Link to online access will be sent 24 hours before the event.

Agenda:

Day 1: Session 1: Barriers to refinement

  • 9:00 - 9:45 AM ET | Keynote on "Orphan" 3Rs | Thomas Hartung, MD, PhD (Johns Hopkins University, USA)
  • 9:45 - 10:05 AM ET | Arguments against using nonhuman primates in research | Jarrod Bailey, PhD (Animal Free Research, UK)
  • 10:10 - 10:30 AM ET | Welfare of primates in laboratories: opportunities for refinement. | Hannah Buchanan-Smith, PhD
  • 10:30 - 10:45 AM ET | Break
  • 10:45 - 11:30 AM ET | How do we effectuate the 3Rs? | Merel Ritskes-Hoitinga, DVM, PhD (Utrecht University, The Netherlands)
  • 11:30 AM - 12:30 PM ET | Interactive guided discussion: Why do we adopt some 3Rs but not others?

12:30 - 1:15 PM ET | Lunch Break

Day 1: Session 2: The right R for the right study

  • 1:15 - 2:00 PM | How temperament assessment and cooperative training organization can facilitate better science | Melanie Graham, MPH, PhD (University of Minnesota, USA)
  • 2:00 - 2:45 PM ET | Performance assessment of a Liver-Chip for prediction of drug-induced liver injury and incorporation within laboratory workflows | Lorna Ewart, CSO (Emulate, USA)
  • 2:45 - 3:00 PM ET | Break
  • 3:00 - 3:45 PM ET | Environmental monitoring for rodents | Megan LaFollette, MS, PhD (The 3Rs Collaborative, USA)
  • 3:45 - 4:45 PM ET | Strategies to implement the 3Rs | Liz Nunamaker, PhD, DVM, DACLAM, DACAW (Global Animal Welfare & Training, Charles River Laboratories, USA)

Day 2: 3Rs Implementation

  • 8:30 - 9:15 AM ET | Practical implementation of enrichment for laboratory zebrafish | TBA
  • 9:15 - 10:00 AM ET | Epidemiological evaluation of the impact of large nests in home cages on mouse health | TBA
  • 10:00 - 10:15 AM ET | Break
  • 10:15 - 11: 00 AM ET | Transitioning from conventional to enriched rodent housing: considerations for implementation | Georgia Mason, PhD (University of Guelph, Canada)
  • 11:00 - 11:45 AM ET | Practical Application of Cumulative Endpoints | TBA

11:45 AM - 12:45 PM ET | Lunch Break

  • 12:45 - 1:30 PM | Pathways to continuous improvement | Steve Niemi, DVM, DACLAM (Boston University, USA)
  • 1:30 - 3:00 PM ET | Panel discussion with USDA/NIH/AAALAC on the 3Rs
    • Gary Borkowski, DVM, MS, DACLAM (AAALAC International, USA)
    • Gwen Maginnis, DVM (USDA-APHIS, Animal Care, USA)
    • Suzanne Fitpatrick, PhD, DABT (FDA, USA)
  • 3:00 - 3:15 PM ET | Break
  • 3:15 - 4:15 PM ET | Breakout Session
  • 4:15 - 4:30 PM ET | Wrap-up of Symposium