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Johns Hopkins Bloomberg School of Public HealthCAAT

CAAT Activities at Society of Toxicology 2020

Email Camila Januario at

More details on the SOT program page

Monday, March 16th

8am - 10:45am
Helena Hogberg
Oligodendrocytes/Schwann Cells: Major Targets in Neurotoxicity and Neurological Diseases
CC Room 303C

10:05am - 10:35am
Isobel Scarisbrick (Mayo Clinic), CAAT Collaborator
Discovery of New Therapeutic Targets for Myelin Regeneration Using Murine and Human Models
CC Roon 303C

11am -12:20pm
Thomas Hartung
Mechanistic Read-Across of Chemical Toxicants Based on Big Data
CC Room 204B

11:10am - 11:20am
Thomas Hartung
Artificial Intelligence: A New Kid on the Block of Toxicology
CC Room 204B

Tuesday, March 17th

8am - 10:45am
Lena Smirnova
Cellular Recovery and Resilience: A New Perspective on Toxicity Testing
CC Ballroom D

10:45am -12:30pm
Vy Tran
Poster: How Complete Is Our Map of the Human Toxome? Functionally Enigmatic Genes as Targets of Chemical Perturbations
Abstract Number/Poster Board number: 2007/ P324
CC Exhibit Hall

1:30pm - 4:15pm
Katya Tsaioun (EBTC), co-chair
Mechanisms and Multiple Exposures: Methods to Tackle Toxicology's Most Difficult Challenges Using Systematic Review Frameworks
CC Ballroom C

Katya Tsaioun
Mechanistic Safety Tests in Decision-Making in the Absence of Human Data: Using a Systematic Review Framework

Daniele Wikoff (ToxStrategies, In., EBTC Scientific Board)
Case Study Applications in the Identification, Assessment, and Integration of Mechanistic Evidence in Human Health Assessments: Consideration of Exposure in Developing Weight of Evidence Conclusions

Wednesday, March 18th

Speaker for Fenna Sille (TBD)
How Sex-Specific Arsenic Immunomodulation Influences Infectious Disease and Cancer Risk
CC Room 304C

Thursday, March 19th

12:30 - 4:00pm​
CC Room 204C

A Society of Toxicology (SOT) Satellite Meeting Organized by the Center for Alternatives to Animal Testing and the Human Toxicology Project Consortium

Please join CAAT and the Human Toxicology Project Consortium (HTPC) for our annual satellite meeting on advancing 21st century toxicology activities. The satellite meeting provides an informal setting in which interested stakeholders can update each other on this important topic. 

The meeting will feature a number of invited presentations but also leave time for an “open microphone” segment in which participants are welcome to make announcements or to comment on germane topics, with or without a few slides.

Tentative Program:

Box lunch (for pre-registered participants only) and 
Welcome, Martin Stephens (Johns Hopkins University)

Invited updates (10-minute talks each followed by up to 5 minutes of discussion)

  • ToxCast - Russell Thomas (EPA)
  • Organ-on-a-chip & Predictive Toxicology Roadmap – Suzanne Fitzpatrick (FDA)
  • Progress in implementing NAMs under TSCA – TBD (EPA)
  • Tox21 – Warren Casey (NIEHS)
  • ICCVAM/NICEATM – Nicole Kleinstreuer (NICEATM)
  • EU Tox-Risk - TBD (Leiden University)
  • AI, iPSC and MPS Projects for Systemic Toxicity – Hajime Kojima (JaCVAM)
  • CAAT Update - Thomas Hartung (Johns Hopkins)
  • Introducing the new HTPC: Animal-Free Safety Assessment - Kate Willett (HSI)

Open microphone for comments, announcements, and discussion


Please register at your earliest convenience here. Box lunches will be available to those who have pre-registered.