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Johns Hopkins Bloomberg School of Public HealthCAAT

CAAT Grants Program


Coordinator: Helena Hogberg (

For Awards information, visit here

CAAT GRANTS: Pre-proposal deadline: May 5th, 2019—maximum grant amount has been changed to $40,000.

CAAT’s research grants program ( is a centerpiece of our work, providing initial funding for scientists to develop alternatives to the use of animals in biomedical research and product safety testing. To date, the center has funded some 300 grants (including renewals) for a total of more than $6 million.

The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) is soliciting projects that focus on the implementation of the NAS Report: Toxicity Testing in the 21st Century: A Vision and a Strategy in the following areas:

  • Proposals Relating to Toxicology: Maximum grant amount is $40,000. The objective should be to significantly reduce or replace laboratory animals. Examples of acceptable projects could include: providing mechanistic understanding of in vitro responses to toxicants in human cells, development of AOPs, or conducting systematic reviews. Consideration should be given to the translation of this new method to evaluate/predict health outcomes.
  • Proposal Relating to Refinement:  See Science-Based Animal Welfare Awards – funded separately.

Although relatively small individually, these grants offer critical seed money that allows researchers to demonstrate the value of a particular area of study so they can gain support from the NIH and other sources.

We have a stringent, peer-reviewed process for selecting the recipients of these grants. This process consists of sending each application to at least four experts in the field from academic, industrial, and government institutions. These reviewers evaluate the applications with regard to scientific merit, budget appropriateness, suitability to CAAT's mission, and expertise of the investigators. They also assign a priority score based on the scoring system used by the NIH.

At the CAAT annual advisory board meeting, these applications are reviewed by board members. Board members constitute the voting contingent for the grant applications and assign priority scores in a secret ballot format based upon a synopsis of the outside reviews and the board reviewers. The applications are then ranked in order of priority score and those that receive fundable scores are awarded funds based upon availability of money for the fiscal year.

We continue to monitor the long-term progress of the Research Grant Program by requiring our grant recipients to submit copies of publications resulting from the work supported by CAAT grant funds. We maintain a list of publications and an archive of journal reprints.

2020-21 Grants: Call for Pre-proposals - CLOSED

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Pre-proposal Details

Pre-proposal Form

During an open period for call for proposals, please click the link below to be taken to the call for proposals and the online proposal submission.

For funding period 2019-20, CAAT granted three projects.

  • Susan Tilton, Oregon State University (new)
    Understanding Combined Effects of Chemical and Non-Chemical Stressors in an In Vitro Respiratory Model
  • Matthias Gossmann, innoVitro GmbH, Germany (new)
    IN FACT: An IN vitro Functional Assay for Cardio Toxicity
  • Andrew Smith, University of Leeds, United Kingdom (new)
    Utilizing novel 3-D bioprinting technology to translate in vitro toxicology findings into complex structures  


centrifuge tubes

Previous Grants

2019-2020 Grants
2018-2019 Grants
2017-2018 Grants
2016-2017 Grants
2015-2016 Grants
2014-2015 Grants
2013-2014 Grants
2012-2013 Grants
2011-2012 Grants
2010-2011 Grants
2009-2010 Grants
2008-2009 Grants
2007-2008 Grants

Previous Grants Archive