- The Scope of Humane Technique: Table of Contents
- Foreword to Special Edition
- Preface
- Scope of the Study
- Integration in the Vertebrate Organism
- Pain and Distress
- The Criteria for and Measurement of Distress
- Man and the Animal World
- Monitoring Animal Experimentation
- The L.A.B. Survey of 1952
- The L.A.B. Data: A Further Analysis
- Results of the Analysis
- The Latest Developments
- Direct and Contingent Inhumanity
- The Analysis of Direct Inhumanity
- The Diagnosis of Disease
- The Removal of Inhumanity: The Three R’s
- Contingent Inhumanity and the Problem of Scale
- Comparative Substitution
- Modes of Absolute and Relative Replacement
- The Principles of Replacement
- The Uses of Tissue Culture
- The Uses of Microorganisms
- Reduction and Strategy in Research
- The Problem with Variance
- The Design and Analysis of Experiments
- The Sources of Physiological Variance
- The Control of Phenotype
- The Control of the Proximate, especially Behavioral Environment
- Neutral and Stressful Studies
- Generally Superimposed Procedures
- The Choice of Procedures
- The Choice of Species
- A Concrete Problem: Experimental Psychiatry and the Humane Study of Fear
- The Personality Factors
- The Sociological Factors
- Special Organizations
- Conclusion
- The Principles of Humane Experimental Technique: References and Source Index
- The Principles of Humane Experimental Technique: Addendum